Publications

2018

Dual spindle formation in zygotes keeps parental genomes apart in early mammalian embryos.
Reichmann J, Nijmeijer B, Hossain MJ, Eguren M, Schneider I, Politi AZ, Roberti MJ, Hufnagel L, Hiiragi T, Ellenberg J.
Science. 2018 Jul 13; 361(6398):189-93. doi: 10.1126/science.aar7462.
[PubMed] [EuroPMC]
[Perspective article in Science] by Agata P. Zielinska and Melina Schuh
Highlighted in [Frankfurter Allgemeine Zeitung], [Zeit], [Süddeutsche] and [EMBL etc.]

Quantitative live and super-resolution microscopy of mitotic chromosomes.
Walther N, Ellenberg J.
Methods Cell Biol. 2018;145:65-90. doi: 10.1016/bs.mcb.2018.03.014. Epub 2018 Apr 24.
[PubMed] [EuroPMC]

Live imaging of cell division in preimplantation mouse embryos using inverted light-sheet microscopy.
Reichmann J, Eguren M, Lin Y, Schneider I, Ellenberg J.
Methods Cell Biol. 2018;145:279-292. doi: 10.1016/bs.mcb.2018.03.030. Epub 2018 Apr 26.
[PubMed] [EuroPMC]

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.
Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Mechtler K, Peters JM.
EMBO J. 2018 Jun 21. pii:e97150. doi: 10.15252/embj.201797150. Epub ahead of print.
[PubMed] [EuroPMC]

Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four dimensional imaging.
Politi AZ, Cai Y, Walther N, Hossain MJ, Koch B, Wachsmuth M, Ellenberg J.
Nat Protoc. 2018 Jun; 13(6):1145-64. doi: 10.1038/nprot.2018.040. Epub 2018 May 24.
[PubMed] [EuroPMC]

Generation and validation of homozygous fluorescent knock-in cells using genome editing.
Koch B, Nijmeijer B, Kueblbeck M, Cai Y, Walther N, Ellenberg J.
Nat Protoc. 2018 Jun; 13(6):1165-87. doi: 10.1038/nprot.2018.042. Epub 2018 May 24.
[PubMed] [EuroPMC]

iNEXT: a European facility network to stimulate translational structural biology.
iNEXT Consortium.
FEBS Lett. 2018 May 15; doi: 10.1002/1873-3468.13062. Epub ahead of print.
[PubMed] [EuroPMC]

A quatitative map of human Condensins provides new insights into mitotic chromosome architecture.
Walther N, Hossain MJ, Politi AZ, Koch B, Kueblbeck M, Oedegaard-Fougner O, Lampe M, Ellenberg J.
J Cell Biol. 2018 Apr 9; doi: 10.1038/jcb.201801048. Epub ahead of print.
[PubMed] [EuroPMC]
[Highlighted in EMBL etc.]
[JCB spotlight article] by Kazuhiro Maeshima, Kayo Hibino and Damien F. Hudson

Fast, robust and precise 3D localization for arbitrary point spread functions.
Li Y, Mund M, Hoess P, Deschamps J, Matti U, Nijmeijer B, Jimenez Sabinina V, Ellenberg J, Schoen I, Ries J.
Nat Methods. 2018 May; 15(5):367-9. doi: 10/1038/nmeth.4661. Epub 2018 Apr 9.
[PubMed] [EuroPMC] [Highlighted in EMBL etc.]

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains.
Xiang W and Roberti MJ, Heriche JK, Huet S, Alexander S, Ellenberg J.
J Cell Biol. 2018 Mar 23; pii: jcb.201709074. Epub ahead of print.
[PubMed] [EuroPMC]

ChromoTrace: Computational reconstruction of 3D chromosome configurations for super-resolution microscopy.
Barton C, Morganella S, Ødegård-Fougner Ø, Alexander S, Ries J, Fitzgerald T, Ellenberg J, Birney E.
PLoS Comput Biol. 2018 Mar 9; 14(3):e1006002.
[PubMed] [EuroPMC]

Postmitotic nuclear pore assembly proceeds by radial dilation of small ER membrane openings.
Otsuka S, Steyer AM, Schorb M, Heriche JK, Hossain MJ, Sethi S, Schwab Y, Beck M, Ellenberg J.
Nat Struct Mol Biol. 2018 Jan; 25(1):21-8. Epub 2017 Nov 27.
[PubMed] [EuroPMC]

Mechanisms of nuclear pore complex assembly - two different ways of building one molecular machine.
Otsuka S & Ellenberg J.
FEBS Lett. 2018 Feb;592(4):475-88. Epub 2017 Nov 8. Review.
[PubMed] [EuroPMC] [See the cover on FEBS letters made by Arina Rybina]

2017

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
Wutz G, Varnai C, Nagasaka K, Cisneros DA, Stocsits R, Tang W, Schoenfelder S, Jessberger G, Muhar M, Hossain JM, Walther N, Koch B, Kueblbeck M, Ellenberg J, Zuber J, Fraser P, Peters JM.
EMBO J. 2017 Dec 15; 36(24): 3573-99. Epub 2017 Dec 7.
[PubMed] [EuroPMC]

[BioRxiv] An experimental and computational framework to build a dynamic protein atlas of human cell division.
Cai Y, Hossain MJ, Heriche JK, Politi AZ, Walther N, Koch B, Wachsmuth M, Nijmeijer B, Kueblbeck M, Martinic M, Ladurner R, Peters JM, Ellenberg J.
In revision. bioRxiv 227751. doi: 10.1101/227751.
[Get the paper from bioRxiv]

Chromosome segregation: Is the spindle all about microtubules.
Schneider I & Lenart P.
Curr Biol. 2017 Nov 6. 27(21):R1168-70. Dispatch.
[PubMed] [EuroPMC]

Real-time chromatin dynamics at the single-cell level during transcription activity.
Germier T, Kocanova S, Walther N, Aurelien B, Shaban HA, Sellou H, Politi A, Ellenberg J, Gallardo F, Bystricky K.
Biophys J. 2017 Oct 3; 113(7):1383-94.
[PubMed] [EuroPMC]

The 4D nucleome project.
Dekker J, Belmont A, Guttman M, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S, 4D Nucleome Network.
Nature. 2017 Sep 13;549(7671):219-26.
[PubMed] [EuroPMC]

2016

Profiling DNA damage response following mitotic perturbations.
Pederson SR, Karemore G, Gudjonsson T, Rask MB, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C.
Nat Commun. 2016 Dec 15; 7:13887.
[PubMed] [EuroPMC]

Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope.
Otsuka S, Bui KH, Schorb M, Hossain MJ, Politi AZ, Koch B, Eltsov M, Beck M, Ellenberg J.
eLife. 2016 Sep 15;5. pii: e19071.
[PubMed] [EuroPMC]

A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, Edwards A, Ellenberg J, Lundberg E, Rimm DL, Rodriguez H, Hiltke T, Snyder M, Yamamoto T.
Nat Methods. 2016 Oct; 13(10):823-7. Epup 2016 Sep 15.
[PubMed] [EuroPMC]

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.
Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW.
Nature. 2016 Jun 29; 535(7611):308-12.
[PubMed] [EuroPMC]

The cellular microscopy phenotype ontology.
Jupp S, Malone J, Burdett T, Heriche JK, Williams E, Ellenberg J, Parkinson H, Rustici G.
J Biomed Semantics. 2016 May 8; 7:28. e Collection 2016.
[PubMed] [EuroPMC]

A protocol for the systematic and quantitative measurement of protein-lipid interactions using the liposome-microarray-based assay.
Saliba AE, Vonkova I, Deghou S, Ceschia S, Tischer C, Kugler KG, Bork P, Ellenberg J, Gavin AC.
Nat Protoc. 2016 Jun; 11(6):1021-38. Epub 2016 May 5.
[PubMed] [EuroPMC]

Sister chromatid resolution is an intrinsic part of chomosome organization in prophase.
Nagasaka K, Hossain MJ, Roberti MJ, Ellenberg J, Hirota T.
Nat Cell Biol. 2016 Jun; 18(6):692-9. Epub 2016 May 2. Erratum in Nat Cell Biol. 2018 Feb 12.
[PubMed] [EuroPMC]

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
Isokane M, Walter T, Mahen R, Nijmejer B, Hériché JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J.
J Cell Biol. 2016 Mar 14;212(6):647-59. Epub 2016 Mar 7.
[PubMed] [EuroPMC]

Inverted light-sheet microscope for imaging mouse pre-implantation development.
Strnad P, Gunther S, Reichmann J, Krzic U, Balazs B, de Medeiros G, Norlin N, Hiiragi T, Hufnagel L, Ellenberg J.
Nature Methods. 2016 Feb;13(2):139-42. Epub 2015 Dec 14.
[PubMed] [EuroPMC] [Highlighted in EMBL etc.]

2015

A cell-based model system links chromotripsis with hyperploidy.
Mardin BR, Drainas AP, Waszak SM, Weischenfeldt J, Isokane M, Stütz AM, Raeder B, Efthymiopoulos T, Buccitelli C, Segura-Wang M, Northcott P, Pfister SM, Lichter P, Ellenberg J, Korbel JO.
Mol Syst Biol. 2015 Sep 28;11(9):828.
[PubMed] [EuroPMC]

Lipid cooperativity as a general membrane-recruitment principle for PH domains.
Vonkova I, Saliba AE, Deghou S, Anand K, Ceschia S, Doerks T, Galih A, Kugler KG, Maeda K, Rybin V, van Noort V, Ellenberg J, Bork P, Gavin AC.
Cell Rep. 2015 Sep 1;12(9):1519-30. Epub 2015 Aug 20.
[PubMed] [EuroPMC]

Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells.
Boni A, Politi AZ, Strnad P, Xiang W, Hossain MJ, Ellenberg J.
J Cell Biol. 2015 Jun 8;209(5):705-20.
[PubMed] [EuroPMC]

High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells.
Wachsmuth M, Conrad C, Bulkescher J, Koch B, Mahen R, Isokane M, Pepperkok R, Ellenberg J.
Nat Biotechnol. 2015 Apr;33(4):384-9. Epub 2015 Mar 16.
[PubMed] [EuroPMC]

FUN-L: Gene prioritization for RNAi screens.
Lees JG, Hériché JK, Morilla I, Fernández JM, Adler P, Krallinger M, Vilo J, Valencia A, Ellenberg J, Ranea JA, Orengo C.
Bioinformatics. 2015 Jun 15;31(12):2052-3. Epub 2015 Feb 8.
[PubMed] [EuroPMC]

Multiple requirements of PLK1 during mouse oocyte maturation.
Solc P, Kitajima T, Yoshida S, Brzakova A, Kaido M, Baran V, Mayer A, Samalova P, Motlik J, Ellenberg J.
PLoS One. 2015 Feb 6;10(2):e0116783. eCollection 2015.
[PubMed] [EuroPMC]

2014

Myo19 ensures symmetric partitioning of mitochondria and coupling of mitochondrial segregation to cell division.
Rohn JL, Patel JV, Neumann B, Bulkescher J, Mchedlishvili N, McMullan RC, Quintero OA, Ellenberg J, Baum B.
Curr Biol. Epup 2014 Nov 3;24(21):2598-605. Epub 2014 Oct 23.
[PubMed] [EuroPMC]

MAP1S controls microtubule stability troughout the cell cycle in human cells.
Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ.
J Cell Sci. 2014 Dec 1;127(12):5007-13. Epup 2014 Oct 9.
[PubMed] [EuroPMC]

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs.
Van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM._
EMBO J. 2014 Nov 18;33(22):2643-58. Epub 2014 Sep 25.
[PubMed] [EuroPMC]

Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells.
Mahen R, Koch B, Wachsmuth M, Politi AZ, Perez-Gonzalez A, Mergenthaler J, Cai Y, Ellenberg J.
Mol Biol Cell. 2014 Nov 5;25(22):3610-8. Epub 2014 Sep 17.
[PubMed] [EuroPMC]

Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation.
Hériché JK, Lees JG, Morilla I, Walter T, Petrova B, Julia Roberti M, Hossain MJ, Adler P, Fernández JM, Krallinger M, Haering CH, Vilo J, Valencia A, Ranea JA, Orengo C, Ellenberg J.
Mol Biol Cell. 2014 Aug 15; 25(16):2522-36. Epub 2014 Jun 18.
[PubMed] [EuroPMC]

Imaging the assembly, structure, and function of the nuclear pore inside cells.
Otsuka S, Szymborska A, Ellenberg J.
Methods Cell Biol. 2014; 122:219-38.
[PubMed] [EuroPMC]

Mechanisms of HsSAS-6 assembly promoting centriole formation in human cells.
Keller D, Orpinell M, Olivier N, Wachsmuth M, Mahen R, Wyss R, Hachet V, Ellenberg J, Manley S, Gönczy P.
J Cell Biol. 2014 Mar 3; 204(5):697-712.
[PubMed] [EuroPMC]

A quantitative liposome microarray to systematically characterize protein-lipid interactions.
Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin AC.
Nat Methods. 2014 Jan; 11(1):47-50. Epub 2013 Nov 24.
[PubMed] [EuroPMC]

2013

Crowded chromatin is not sufficient for heterochromatin formation and not required for its maintenance.
Walter A, Chapuis C, Huet S, Ellenberg J.
J Struct Biol. 2013 Dec;184(3):445-53. Epub 2013 Oct 18.
[PubMed] [EuroPMC]

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.
Pau G, Walter T, Neumann B, Heriche JK, Ellenberg J, Huber W.
BMC Bioinformatics. 2013 Oct 16;14(1):308.
[PubMed] [EuroPMC] [Mitocheck]

Wapl is an essential regulator of chromatin structure and chromosome segregation.
Tedeschi A, Wutz G, Huet S, Jaritz M, Wuensche A, Schirghuber E, Davidson IF, Tang W, Cisneros DA, Bhaskara V, Nishiyama T, Vaziri A, Wutz A, Ellenberg J, Peters JM.
Nature. 2013 Sep 26;501(7468):564-8. Epub 2013 Aug 25.
[PubMed] [EuroPMC]

Nuclear Pore Scaffold Structure Analyzed by Super-Resolution Microscopy and Particle Averaging
Szymborska A, de Marco A, Daigle N, Cordes VC, Briggs JAG, Ellenberg J.
Science. 2013 Aug 9;341(6146):655-8. Epub 2013 Jul 11.
[PubMed] [EuroPMC]

EGF-induced centrosome separation promotes mitotic progression and cell survival.
Mardin BR, Isokane M, Cosenza MR, Krämer A, Ellenberg J, Fry AM, Schiebel E.
Dev Cell. 2013 May 13;25(3):229-40. Epub 2013 May 2.
[PubMed] [EuroPMC]

2012

GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration.
Scolz M, Widlund PO, Piazza S, Bublik DR, Reber S, Peche LY, Ciani Y, Hubner N, Isokane M, Monte M, Ellenberg J, Hyman AA, Schneider C, Bird AW.
PLoS One. 2012;7(12):e51259. Epub 2012 Dec 7.
[PubMed] [EuroPMC]

Mitotic lamin disassembly is triggered by lipid-mediated signaling
Mall M, Walter T, Gorjánácz M, Davidson IF, Nga Ly-Hartig TB, Ellenberg J, Mattaj IW.
J Cell Biol. 2012 Sep 17;198(6):981-90.
[PubMed] [EuroPMC]

The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development.
Courtois A, Schuh M, Ellenberg J, Hiiragi T.
J Cell Biol. 2012 Aug 6;198(3):357-70. Epub 2012 Jul 30.
[EuroPMC]

A fractal model for nuclear organization: current evidence and biological implications.
Bancaud A, Lavelle C, Huet S, Ellenberg J.
Nucleic Acids Res.2012 Oct;40(18):8783-92. Epub 2012 Jul 11.
[PubMed] [EuroPMC]

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.
Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R.
Nat Cell Biol. 2012 Jun 3;14(7):764-74.
[PubMed] [EuroPMC]

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.
Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J.
Cell Death Differ. 2012 May;19(5):798-807. Epub 2011 Nov 11.
[PubMed] [EuroPMC]

2011

The quantitative proteome of a human cell line
Beck M, Schmidt A, Malmstroem J, Claassen M, Ori A, Szymborska A, Herzog F, Rinner O, Ellenberg J, Aebersold R.
Mol Syst Biol. 2011 Nov 8; 7:549.
[PubMed] [EuroPMC]

Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes
Kitajima TS, Ohsugi M, Ellenberg J.
Cell. 2011 Aug 19;146(4):568-581.
[PubMed] [EuroPMC] [Database]

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of Src kinases.
Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W.
Genome Res. 2011 Nov;21(11):1955-68. Epub 2011 Jul 27.
[PubMed] [EuroPMC]

A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells.
Ng K, Daigle N, Bancaud A, Ohhata T, Humphreys P, Walker R, Ellenberg J, Wutz A.
Mol Biol Cell. 2011 Jul;22(14):2634-2645. Epub 2011 May 25.
[PubMed] [EuroPMC]

Automatic Quantification of Microtubule Dynamics Enables RNAi-screening of New Mitotic Spindle Regulators.
Sironi L, Solon J, Conrad C, Mayer TU, Brunner D, Ellenberg J.
Cytoskeleton (Hoboken). 2011 May;68(5):266-78. Epub 2011 Apr 13.
[PubMed] [EuroPMC]

A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear envelope in prophase.
Bolhy S, Bouhlel I, Dultz E, Nayak T, Zuccolo M, Gatti X, Vallee R, Ellenberg J, Doye V.
J Cell Biol. 2011 Mar 7;192(5):855-71.
[PubMed] [EuroPMC]

Micropilot: automation of fluorescence microscopy-based imaging for systems biology.
Conrad C, Wunsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, Ellenberg J.
Nat Methods. 2011 Mar;8(3):246-9. Epub 2011 Jan 23.
[PubMed] [EuroPMC] [Micropilot]

Intracellular transport by an anchored homogeneously contracting F-actin meshwork.
Mori M, Monnier N, Daigle N, Bathe M, Ellenberg J, Lénárt P.
Curr. Biol. 2011 Apr 12;21(7):606-11.
[PubMed] [EuroPMC]

Before 2011

2010

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response.
Landsverk HB, Mora-Bermudez F, Landsverk OJ, Hasvold G, Naderi S, Bakke O, Ellenberg J, Collas P, Syljuasen RG & Kuntziger T.
EMBO Rep. 2010 Nov;11(11):868-75. Epub 2010 Oct 1.
[PubMed] [EuroPMC]

Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase.
Dultz E, Ellenberg J.
J Cell Biol. 2010 Oct 4;191(1):15-22. Epub 2010 Sep 27.
[PubMed] [EuroPMC]

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.
Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW.
Nat Methods. 2010 Aug 8.
[PubMed] [EuroPMC] [CellCognition]

Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Hutchins JR, Toyoda Y, Hegemann B, Poser I, Heriche JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM.
Science. 2010 Apr 30;328(5978):593-9. Epub 2010 Apr 1.
[PubMed] [EuroPMC] [MitoCheck]

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.
Neumann B, Walter T, Heriche JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J.
Nature. 2010 Apr 1;464(7289):721-7.
[PubMed] [EuroPMC] [MitoCheck]

Visualization of image data from cells to organisms.
Walter T, Shattuck DW, Baldock R, Bastin ME, Carpenter AE, Duce S, Ellenberg J, Fraser A, Hamilton N, Pieper S, Ragan MA, Schneider JE, Tomancak P, Heriche JK.
Nat Methods. 2010 Mar;7(3 Suppl):S26-41.
[PubMed] [EuroPMC]

Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy.
Huet S, Avilov SV, Ferbitz L, Daigle N, Cusack S, Ellenberg J.
J Virol. 2010 Feb;84(3):1254-64. Epub 2009 Nov 11.
[PubMed] [EuroPMC]

High-throughput microscopy using live mammalian cells. Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J.
In 'Live Cell Imaging: A Laboratory Manual', Second Edition, 2010 (eds. R.D. Goldman, J.R. Swedlow & D.L. Spector). Cold Spring Harbor Laboratory Press, Cold Spring Harbor
[PubMed] [EuroPMC]

Fluorescence-Perturbation Techniques to Study Mobility and Molecular Dynamics of Proteins in Live Cells.
Bancaud A, Huet S, Rabut G, Ellenberg J.
In 'Live Cell Imaging: A Laboratory Manual', Second Edition, 2010 (eds. R.D. Goldman, J.R. Swedlow & D.L. Spector). Cold Spring Harbor Laboratory Press, Cold Spring Harbor
[PubMed] [EuroPMC]

2009

Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin.
Bancaud A, Huet S, Daigle N, Mozziconacci J, Beaudouin J, Ellenberg J.
EMBO J. 2009 Dec 16;28(24):3785-98.
[PubMed] [EuroPMC]

Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time.
Harder N, Mora-Bermudez F, Godinez WJ, Wünsche A, Eils R, Ellenberg J, Rohr K.
Genome Res. 2009 Nov;19(11):2113-24. Epub 2009 Oct 1.
[PubMed] [EuroPMC]

Formation of the nuclear envelope permeability barrier studied by sequential photoswitching and flux analysis.
Dultz E, Huet S, Ellenberg J.
Biophys J. 2009 Oct 7;97(7):1891-7.
[PubMed] [EuroPMC]

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging.
Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J.
J Struct Biol. 2009 Oct 23.
[PubMed] [EuroPMC]

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C.
Cell. 2009 Feb 6;136(3):435-46.
[PubMed] [EuroPMC]

Chromophore-Assisted Laser Inactivation of alpha- and gamma-Tubulin SNAP-tag Fusion Proteins inside Living Cells.
Keppler A, Ellenberg J.
ACS Chem Biol. 2009 Feb 3.
[PubMed] [EuroPMC]

2008

A new model for asymmetric spindle positioning in mouse oocytes.
Schuh M, Ellenberg J.
Curr Biol. 2008 Dec 23;18(24):1986-92. Epub 2008 Dec 8.
[PubMed] [EuroPMC]

Sun1 forms immobile macromolecular assemblies at the nuclear envelope.
Lu W, Gotzmann J, Sironi L, Jaeger VM, Schneider M, Luke Y, Uhlen M, Szigyarto CA, Brachner A, Ellenberg J, Foisner R, Noegel AA, Karakesisoglou I.
Biochim Biophys Acta. 2008 Dec;1783(12):2415-26. Epub 2008 Sep 19.
[PubMed] [EuroPMC]

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates.
Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R.
J Biomol Screen. 2008 Aug;13(7):575-80. Epub 2008 Jul 3.
[PubMed] [EuroPMC]

Nuclear pore complex assembly through the cell cycle: regulation and membrane organization.
Antonin W, Ellenberg J, Dultz E.
FEBS Lett. 2008 Jun 18;582(14):2004-16. Epub 2008 Mar 6.
[PubMed] [EuroPMC]

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.
Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ.
J Cell Sci. 2008 May 15;121(Pt 10):1718-26. Epub 2008 Apr 29.
[PubMed] [EuroPMC]

Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells.
Dultz E, Zanin E, Wurzenberger C, Braun M, Rabut G, Sironi L, Ellenberg J.
J Cell Biol. 2008 Mar 10;180(5):857-65. Epub 2008 Mar 3.
[PubMed] [EuroPMC]

2007

Self-organization of MTOCs replaces centrosome function during acentrosomal spindle assembly in live mouse oocytes.
Schuh M, Ellenberg J.
Cell. 2007 Aug 10;130(3):484-98.
[PubMed] [EuroPMC]

Lambda(N)-GFP: an RNA reporter system for live-cell imaging.
Daigle N, Ellenberg J.
Nat Methods. 2007 Aug;4(8):633-6. Epub 2007 Jul 1.
[PubMed] [EuroPMC]

Maximal chromosome compaction occurs by axial shortening in anaphase and depends on Aurora kinase.
Mora-Bermudez F, Gerlich D, Ellenberg J.
Nat Cell Biol. 2007 Jul;9(7):822-31. Epub 2007 Jun 10.
[PubMed] [EuroPMC]

An RNAi screening platform to identify secretion machinery in mammalian cells.
Simpson JC, Cetin C, Erfle H, Joggerst B, Liebel U, Ellenberg J, Pepperkok R.
J Biotechnol. 2007 Apr 30;129(2):352-65. Epub 2007 Jan 14.
[PubMed] [EuroPMC]

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ.
Nat Struct Mol Biol. 2007 Mar;14(3):229-33. Epub 2007 Feb 25.
[PubMed] [EuroPMC]

Measuring structural dynamics of chromosomes in living cells by fluorescence microscopy.
Mora-Bermudez F, Ellenberg J.
Methods. 2007 Feb;41(2):158-67.
[PubMed] [EuroPMC]

Reverse transfection on cell arrays for high content screening microscopy.
Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R.
Nat Protoc. 2007;2(2):392-9.
[PubMed] [EuroPMC] [Mitocheck]

2006

Minimizing the risk of reporting false positives in large-scale RNAi screens.
Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, Ma Y, Mathey-Prevot B, Root DE, Sabatini DM, Taipale J, Perrimon N, Bernards R.
Nat Methods. 2006 Oct;3(10):777-9.
[PubMed] [EuroPMC]

Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication.
Gerlich D, Koch B, Dupeux F, Peters JM, Ellenberg J.
Curr Biol. 2006 Aug 8;16(15):1571-8.
[PubMed] [EuroPMC]

Fluorophores for live cell imaging of AGT fusion proteins across the visible spectrum.
Keppler A, Arrivoli C, Sironi L, Ellenberg J.
Biotechniques. 2006 Aug;41(2):167-70, 172, 174-5.
[PubMed] [EuroPMC]

Resolution of chiasmata in oocytes requires separase-mediated proteolysis.
Kudo NR, Wassmann K, Anger M, Schuh M, Wirth KG, Xu H, Helmhart W, Kudo H, McKay M, Maro B, Ellenberg J, de Boer P, Nasmyth K.
Cell. 2006 Jul 14;126(1):135-46.
[PubMed] [EuroPMC]

NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules.
Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Kocher T, Gentzel M, Gorlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW.
Mol Biol Cell. 2006 Jun;17(6):2646-60. Epub 2006 Mar 29.
[PubMed] [EuroPMC]

Nuclear actin: a lack of export allows formation of filaments.
Schuh M, Ellenberg J.
_Curr Biol. 2006 May 9;16(9):R321-3.
[PubMed] [EuroPMC]

High-throughput RNAi screening by time-lapse imaging of live human cells.
Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J.
Nat Methods. 2006 May;3(5):385-90.
[PubMed] [EuroPMC] [Mitocheck]

Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins.
Beaudouin J, Mora-Bermudez F, Klee T, Daigle N, Ellenberg J.
Biophys J. 2006 Mar 15;90(6):1878-94. Epub 2005 Dec 30.
[PubMed] [EuroPMC]

Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.
Gerlich D, Hirota T, Koch B, Peters JM, Ellenberg J.
Curr Biol. 2006 Feb 21;16(4):333-44.
[PubMed] [EuroPMC]

Monitoring the permeability of the nuclear envelope during the cell cycle.
Lenart P, Ellenberg J.
Methods 2006 Jan;38(1):17-24.
[PubMed] [EuroPMC]

High-throughput fluorescence microscopy for systems biology.
Pepperkok R, Ellenberg J.
Nat Rev Mol Cell Biol 2006 9(7) 690-6.
[PubMed] [EuroPMC]

2005

A contractile nuclear actin network drives chromosome congression in oocytes.
Lenart P, Bacher CP, Daigle N, Hand AR, Eils R, Terasaki M, Ellenberg J.
Nature 2005 Aug 11;436(7052):812-8. Epub 2005 Jul 13.
[PubMed] [EuroPMC] [Cover]

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35.
Chusainow J, Ajuh PM, Trinkle-Mulcahy L, Sleeman JE, Ellenberg J, Lamond AI.
RNA 2005 Aug;11(8):1201-14.
[PubMed] [EuroPMC]

Photobleaching techniques to study mobility and molecualr dynamics of proteins in live cells: FRAP, iFRAP and FLIP.
Rabut G, Ellenberg J.
In "Live Cell Imaging: A Laboratory Manual Vol. 1", Goldman, R.D. and Spector, D.L., (Eds.), 101-127. Cold Spring Harbor Laboratory Press, Col Spring Harbor, 2005.

2004

Distinct functions of condensin I and II in mitotic chromosome assembly.
Hirota T, Gerlich D, Koch B, Ellenberg J, Peters JM.
J Cell Sci 2004 Dec 15;117(Pt 26):6435-45. Epub 2004 Nov 30.
[PubMed] [EuroPMC]

LAP2alpha and BAF transiently localize to telomeres and specific regions on chromatin during nuclear assembly.
Dechat T, Gajewski A, Korbei B, Gerlich D, Daigle N, Haraguchi T, Furukawa K, Ellenberg J, Foisner R.
J Cell Sci 2004 Dec 1;117(Pt 25):6117-28. Epub 2004 Nov 16.
[PubMed] [EuroPMC]

Mapping the dynamic organization of the nuclear pore complex inside single living cells.
Rabut G, Doye V, Ellenberg J.
Nat Cell Biol 2004 Nov;6(11):1114-21. Epub 2004 Oct 24.
[PubMed] [EuroPMC]

Automatic real-time three-dimensional cell tracking by fluorescence microscopy.
Rabut G, Ellenberg J.
J Microsc 2004 Nov;216(Pt 2):131-7.
[PubMed] [EuroPMC]

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles.
Sumara I, Gimenez-Abian JF, Gerlich D, Hirota T, Kraft C, de la Torre C, Ellenberg J, Peters JM.
Curr Biol 2004 Oct 5;14(19):1712-22.
[PubMed] [EuroPMC]

Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei.
Bubulya PA, Prasanth KV, Deerinck TJ, Gerlich D, Beaudouin J, Ellisman MH, Ellenberg J, Spector DL.
J Cell Biol 2004 Oct 11;167(1):51-63.
[PubMed] [EuroPMC]

Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells.
Leung AK, Gerlich D, Miller G, Lyon C, Lam YW, Lleres D, Daigle N, Zomerdijk J, Ellenberg J, Lamond AI.
J Cell Biol 2004 Sep 13;166(6):787-800. Epub 2004 Sep 07.
[PubMed] [EuroPMC]

Calcium rises locally trigger focal adhesion disassembly and enhance residency of focal adhesion kinase at focal adhesions.
Giannone G, Ronde P, Gaire M, Beaudouin J, Haiech J, Ellenberg J, Takeda K.
J Biol Chem 2004 Jul 2;279(27):28715-23. Epub 2004 Apr 21.
[PubMed] [EuroPMC]

Regulation of sister chromatid cohesion between chromosome arms.
Gimenez-Abian JF, Sumara I, Hirota T, Hauf S, Gerlich D, de la Torre C, Ellenberg J, Peters JM.
Curr Biol 2004 Jul 13;14(13):1187-93.
[PubMed] [EuroPMC]

Dynamics of nuclear pore complex organization through the cell cycle.
Rabut G, Lenart P, Ellenberg J.
Curr Opin Cell Biol 2004 Jun;16(3):314-21.
[PubMed] [EuroPMC]

Automatic identification of subcellular phenotypes on human cell arrays.
Conrad C, Erfle H, Warnat P, Daigle N, Lorch T, Ellenberg J, Pepperkok R, Eils R.
Genome Res 2004 Jun;14(6):1130-6.
[PubMed] [EuroPMC]

The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis.
Loiodice I, Alves A, Rabut G, Van Overbeek M, Ellenberg J, Sibarita JB, Doye V.
Mol Biol Cell 2004 Jul;15(7):3333-44.
[PubMed] [EuroPMC]

RanBP2/Nup358 Provides a Major Binding Site for NXF1-p15 Dimers at the Nuclear Pore Complex and Functions in Nuclear mRNA Export.
Forler D, Rabut G, Ciccarelli FD, Herold A, Kocher T, Niggeweg R, Bork P, Ellenberg J, Izaurralde E.
Mol Biol Cell 2004 Feb;24(3):1155-67.
[PubMed] [EuroPMC]**

Light microscopy of echinoderm embryos.
Strickland L, von Dassow G, Ellenberg J, Foe V, Lenart P, Burgess D.
Methods Cell Biol 2004;74:371-409.
[PubMed] [EuroPMC]

2003

Dynamics of chromosome positioning during the cell cycle.
Gerlich D, Ellenberg J.
Curr Opin Cell Biol 2003 Dec;15(6):664-71.
[PubMed] [EuroPMC]

NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization.
Raemaekers T, Ribbeck K, Beaudouin J, Annaert W, Van Camp M, Stockmans I, Smets N, Bouillon R, Ellenberg J, Carmeliet G.
J Cell Biol 2003 Sep 15;162(6):1017-29.
[PubMed] [EuroPMC]

4D imaging to assay complex dynamics in live specimens.
Gerlich D, Ellenberg J.
Nat Cell Biol 2003 Sep;Suppl:S14-9.
[PubMed] [EuroPMC]

Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes.
Lénart P, Rabut G, Daigle N, Hand AR, Terasaki M, Ellenberg J.
J Cell Biol 2003 Mar 31;160(7):1055-68.
[PubMed] [EuroPMC]

Global chromosome positions are transmitted through mitosis in mammalian cells.
Gerlich D, Beaudouin J, Kalbfuss B, Daigle N, Eils R, Ellenberg J.
Cell 2003 Mar 21;112(6):751-64.
[PubMed] [EuroPMC]

Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling.
Reid G, Hubner MR, Metivier R, Brand H, Denger S, Manu D, Beaudouin J, Ellenberg J, Gannon F.
Mol Cell 2003 Mar;11(3):695-707.
[PubMed] [EuroPMC]

Nuclear envelope dynamics in oocytes: from germinal vesicle breakdown to mitosis.
Lenart P, Ellenberg J.
Curr Opin Cell Biol 2003 Feb;15(1):88-95.
[PubMed] [EuroPMC]

2002

Ribonucleoprotein-dependent localization of the yeast class V myosin Myo4p.
Kruse C, Jaedicke A, Beaudouin J, Bohl F, Ferring D, Guttler T, Ellenberg J, Jansen RP.
J Cell Biol 2002 Dec 23;159(6):971-82.
[PubMed] [EuroPMC]

Chromosomal association of Ran during meiotic and mitotic divisions.
Hinkle B, Slepchenko B, Rolls MM, Walther TC, Stein PA, Mehlmann LM, Ellenberg J, Terasaki M.
J Cell Sci 2002 Dec 1;115(Pt 23):4685-93.
[PubMed] [EuroPMC]

Remodelling the walls of the nucleus.
Burke B, Ellenberg J.
Nat Rev Mol Cell Biol 2002 Jul;3(7):487-97.
[PubMed] [EuroPMC]

Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation.
Schmitt A, Gutierrez GJ, Lenart P, Ellenberg J, Nebreda AR.
FEBS Lett 2002 May 8;518(1-3):23-8.
[PubMed] [EuroPMC]

Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina.
Beaudouin J, Gerlich D, Daigle N, Eils R, Ellenberg J.
Cell 2002 Jan 11;108(1):83-96.
[PubMed] [EuroPMC]

Dynamics of nuclear envelope proteins during the cell cycle in mammalian cells.
Ellenberg J.
In "Dynamics of Nuclear Envelope Assembly in Embryos and Somatic Cells, Vol. 23", P. Collas (ed), 18-25. Landes Biosciences, Georgetown, Texas, USA, 2002. 

2001

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.
Belgareh N, Rabut G, Bai SW, van Overbeek M, Beaudouin J, Daigle N, Zatsepina OV, Pasteau F, Labas V, Fromont-Racine M, Ellenberg J, Doye V.
J Cell Biol 2001 Sep 17;154(6):1147-60.
[PubMed] [EuroPMC]

Four-dimensional imaging and quantitative reconstruction to analyse complex spatiotemporal processes in live cells.
Gerlich D, Beaudouin J, Gebhard M, Ellenberg J, Eils R.
Nat Cell Biol 2001 Sep;3(9):852-5.
[PubMed] [EuroPMC]

Nuclear pore complexes form immobile networks and have a very low turnover in live mammalian cells.
Daigle N, Beaudouin J, Hartnell L, Imreh G, Hallberg E, Lippincott-Schwartz J, Ellenberg J.
J Cell Biol 2001 Jul 9;154(1):71-84.
[PubMed] [EuroPMC]

Nucleocytoplasmic transport: diffusion channel or phase transition?
Rabut G, Ellenberg J.
Curr Biol 2001 Jul 24;11(14):R551-4.
[PubMed] [EuroPMC]

A new model for nuclear envelope breakdown.
Terasaki M, Campagnola P, Rolls MM, Stein PA, Ellenberg J, Hinkle B, Slepchenko B.
Mol Biol Cell 2001 Feb;12(2):503-10.
[PubMed] [EuroPMC]

2000

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition.
Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K.
Mol Cell Biol 2000 Sep;20(17):6537-49
[PubMed] [EuroPMC]

Dynamics and retention of misfolded proteins in native ER membranes
Nehls S, Snapp EL, Cole NB, Zaal KJ, Kenworthy AK, Roberts TH, Ellenberg J, Presley JF, Siggia E, Lippincott-Schwartz J.
Nat Cell Biol 2000 May;2(5):288-95
[PubMed] [EuroPMC]

1999

Golgi membranes are absorbed into and reemerge from the ER during mitosis
Zaal KJ, Smith CL, Polishchuk RS, Altan N, Cole NB, Ellenberg J, Hirschberg K, Presley JF, Roberts TH, Siggia E, Phair RD, Lippincott-Schwartz J.
Cell 1999 Dec 10;99(6):589-601
[PubMed] [EuroPMC]

Dynamics and mobility of nuclear envelope proteins in interphase and mitotic cells revealed by green fluorescent protein chimeras.
Ellenberg J, Lippincott-Schwartz J.
Methods 1999 Nov;19(3):362-72
[PubMed] [EuroPMC]

Intracellular trafficking of emerin, the Emery-Dreifuss muscular dystrophy protein.
Ostlund C, Ellenberg J, Hallberg E, Lippincott-Schwartz J, Worman HJ.
J Cell Sci 1999 Jun;112 ( Pt 11):1709-19
[PubMed] [EuroPMC]

Dual-colour imaging with GFP variants.
Ellenberg J, Lippincott-Schwartz J, Presley JF.
Trends Cell Biol 1999 Feb;9(2):52-6
[PubMed] [EuroPMC]

Monitoring the dynamics and mobility of membrane proteins tagged with green fluorescent protein.
Lippincott-Schwartz J, Presley JF, Zaal KJ, Hirschberg K, Miller CD, Ellenberg J.
Methods Cell Biol 1999;58:261-81
[PubMed] [EuroPMC]

1998

Kinetic analysis of secretory protein traffic and characterization of golgi to plasma membrane transport intermediates in living cells.
Hirschberg K, Miller CM, Ellenberg J, Presley JF, Siggia ED, Phair RD, Lippincott-Schwartz J.
J Cell Biol 1998 Dec 14;143(6):1485-503
[PubMed] [EuroPMC]

ZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulation.
Sloan-Lancaster J, Presley J, Ellenberg J, Yamazaki T, Lippincott-Schwartz J, Samelson LE.
J Cell Biol 1998 Nov 2;143(3):613-24
[PubMed] [EuroPMC]

Two-color green fluorescent protein time-lapse imaging.
Ellenberg J, Lippincott-Schwartz J, Presley JF.
Biotechniques 1998 Nov;25(5):838-42, 844-6
[PubMed] [EuroPMC]

Retrograde transport of Golgi-localized proteins to the ER.
Cole NB, Ellenberg J, Song J, DiEuliis D, Lippincott-Schwartz J.
J Cell Biol 1998 Jan 12;140(1):1-15
[PubMed] [EuroPMC]

1997

Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis.
Ellenberg J, Siggia ED, Moreira JE, Smith CL, Presley JF, Worman HJ, Lippincott-Schwartz J.
J Cell Biol 1997 Sep 22;138(6):1193-206
[PubMed] [EuroPMC]

The transmembrane domain of a carboxyl-terminal anchored protein determines localization to the endoplasmic reticulum.
Yang M, Ellenberg J, Bonifacino JS, Weissman AM.
J Biol Chem 1997 Jan 17;272(3):1970-5
[PubMed] [EuroPMC]

Fluorescence photobleaching techniques.
Ellenberg J, Lippincott-Schwartz J.
In "Cells: A Laboratory Manual, Vol. 2", Spector, D., Goldman, R. & Leinwand, L. (Eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1997, 79.1-79.23